Program

 

Day 1

April 3rd (BMC lecture halls B8 and B10)

 

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8:30 – 8:55      Registration. B10.

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Symposium in B8:

9:00 – 9:05    Welcome note.

9:05 – 9:25      What is the latest in Long-Read Sequencing technologies at NGI? 

 

SESSION 1 – INTRODUCTION to technologies and research highlights. B8.

9:25 – 9:50       Company presentation: 10X Genomics.

9:50 – 10:15      Company presentation: Oxford Nanopore.

10:15 - 10:40     Company presentation: PacBio.

 

10:40 – 11:00    Coffee break, B10

 

SESSION 1, continued: INTRODUCTION to technologies and research highlights. B8.

11:00 – 11:30     KEYNOTE SPEAKER - Sonja Vernes, Max Planck. The Bat1K Project: Bat Genomes, Biology, and Implications.

11:30 – 11:50      Mohamed Zouine, INRA/ENSAT. Long DNA molecule sequencing: from  de novo assembly to chromosome level scaffolding of the tomato and melon genomes.

11:50 – 12:10      Ida Höijer, UU. New approaches for long-read targeted sequencing.

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12:10 - 13:15     LUNCH in B10.

 

SESSION 2: Human genomics & medicine, B8 

13:15 – 13:45      KEYNOTE SPEAKER - Alexander Hoischen, Radboud UMC. Medical genetics: Identification of hidden structural variants with long-read sequencing.

13:45 – 14:05    Yahya Anvar, Leiden University Medical Center. Long-reads paving the way to personalized therapeutics.

14:05 – 14:25    Lucia Cavelier, Uppsala University - Uppsala Academic Hospital. Long read sequencing in clinical applications.

14:25 – 14:45    Wigard Kloosterman, UM Utrecht. Unraveling human genome structure using long-read Nanopore sequencing.

 

14:45 – 15:15    Coffee, company booths open for presentations. B10.

 

SESSION 3: Non-model organisms & biodiversity, B8

15:15 – 15:45     KEYNOTE SPEAKER -Kerstin Howe, Sanger. Sequencing the Tree of Life: The Sanger Darwin Project.

15:45 - 16:05    Matt Webster, Uppsala University. A chromosome-level hybrid assembly of the honeybee genome.

16:05 – 16:25    Niklas Mähler, Umeå University. Long-read assembly of Norway spruce and Scots pine.

16:25 – 16:45    Åsa Sjöling, KI. SMRT analysis of plasmid gene content and methylation profiles within clonal lineages of enterotoxigenic Escherichia coli (ETEC).

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16:45 - 17:05    Wilfried Haerty, Earlham Institute. Characterization of splicing diversity and gene fusions through Nanopore sequencing.

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17:05 - 17:10     Closing day 1

17:10 - 18:30     Mingle and bar. B10.

 

 

Day 2

April 4th (Trippelrummet at Navet)

 

9:00 – 9:05    Introduction to Day2 workshops.

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Workshop 1: General analysis of Long-read data

9:05 - 9:30  Stephen Rudd, ONT

9:30 - 9:55   Armin Töpfer, PacBio

9:55 - 10:20 Fanny Taborsak-Lines; NGI-Stockholm. Development of methods for linked-read sequencing.

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10:20 - 10:45 Coffee break, Navet

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Workshop 2: Structural variation

10:45 - 11:15 KEYNOTE: Alexander Hoischen, Radboud UMC. Application of long-read data for structural variation studies.

11:15 - 11:35 Jesper Eisfeldt, KI. Analysis of structural variation with 10x Genomics data in rare human diseases.

11:35 - 11:55 Adam Ameur, NGI-Uppsala. Novel sequences and structural variation in two SweGen individuals.

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12:00 - 13:00  Lunch and informal mingle

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Workshop 3: De novo assembly with long reads

13:00 - 13:30 KEYNOTE: Kerstin Howe, Sanger Institute. Genome Assembly Validation: Common Assembly Issues and Strategies for Improvements.

13:30 - 13:50 Ignas Bunikis, NGI-Uppsala. Hybrid assembly of long-read data.

13:50 - 14:10 Merce Montoliu Nerin, UU. Single nuclei to whole genome assemblies of Arbuscular Mycorrhizal fungi.

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14:10 - 15:15   Panel discussion: combination of long read technologies for de novo an structural variation studies.

15:15 - Closing the meeting

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